Does xylitol (a common ingredient in many toothpastes, chewing gums, and breath mints) cause problems in the oral microbiome, the gut, and/or the rest of the body?
Does it increase our risk of cardiovascular disease and other health issues?
In this video, we dive deep into the science to uncover the truth about xylitol’s impact on the oral and gut microbiomes, the impact xylitol can have on children’s oral health, and what’s going on with the infamous study that suggested a possible link between xylitol and cardiovascular health.
Timestamps
- 01:47 – What is xylitol?
- 02:34 – What’s the oral microbiome, & why is it important for oral health?
- 04:13 – Xylitol’s impact on the oral microbiome
- 09:44 – How xylitol can help support children’s oral health
- 13:32 – Xylitol’s impact on human gut health
- 19:15 – Our thoughts on the xylitol/cardiovascular disease study
Helpful, Related Resources
- How to Optimize Your Oral Microbiome [FREE eBook]
- Are Essential Oils Safe to Use in the Mouth? [video resource]
- Is Glycerin in Toothpaste Bad for Your Teeth? [video resource]
- How to Balance Your Oral Flora and Be a Good Conductor of the Symphony in Your Mouth
- How to Avoid 3 Common Sources of Gum Disease [video resource]
- Is Xylitol Safe to Brush with? [video resource]
- OraWellness Blog
- OraWellness eBook Library
- Shine Remineralizing Tooth Whitening Powder [product solution]
- OraWellness Floss [product solution]
Other Resources:
- Mäkinen, Kauko K. Sugar Alcohols, Caries Incidence, and Remineralization of Caries Lesions: A Literature Review. 2010 Jan. doi: 10.1155/2010/981072
- Maguire, A., Rugg-Gunn, A. Xylitol and caries prevention — is it a magic bullet?. Br Dent J 194, 429–436 (2003). doi.org/10.1038/sj.bdj.4810022
- Miake Y, Saeki Y, Takahashi M, Yanagisawa T. Remineralization effects of xylitol on demineralized enamel. J Electron Microsc (Tokyo). 2003;52(5):471-6. doi: 10.1093/jmicro/52.5.471. PMID: 14700079
- Nayak PA, Nayak UA, Khandelwal V. The effect of xylitol on dental caries and oral flora. Clin Cosmet Investig Dent. 2014 Nov 10;6:89-94. doi: 10.2147/CCIDE.S55761. PMID: 25422590; PMCID: PMC4232036
- Söderling E, Isokangas P, Pienihäkkinen K, Tenovuo J. Influence of maternal xylitol consumption on acquisition of mutans streptococci by infants. J Dent Res. 2000 Mar;79(3):882-7. doi: 10.1177/00220345000790031601. PMID: 10765964
- Söderling E, Isokangas P, Pienihäkkinen K, Tenovuo J, Alanen P. Influence of maternal xylitol consumption on mother-child transmission of mutans streptococci: 6-year follow-up. Caries Res. 2001 May-Jun;35(3):173-7. doi: 10.1159/000047452. PMID: 11385196
- Salli K, Lehtinen MJ, Tiihonen K, Ouwehand AC. Xylitol’s Health Benefits beyond Dental Health: A Comprehensive Review. Nutrients. 2019 Aug 6;11(8):1813. doi: 10.3390/nu11081813. PMID: 31390800; PMCID: PMC6723878
- Sato T, Kusuhara S, Yokoi W, Ito M, Miyazaki K. Prebiotic potential of L-sorbose and xylitol in promoting the growth and metabolic activity of specific butyrate-producing bacteria in human fecal culture. FEMS Microbiol Ecol. 2017 Jan;93(1):fiw227. doi: 10.1093/femsec/fiw227. Epub 2016 Nov 2. PMID: 27810878
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- Canani RB, Costanzo MD, Leone L, Pedata M, Meli R, Calignano A. Potential beneficial effects of butyrate in intestinal and extraintestinal diseases. World J Gastroenterol. 2011 Mar 28;17(12):1519-28. doi: 10.3748/wjg.v17.i12.1519. PMID: 21472114; PMCID: PMC3070119
- Hosseini E, Grootaert C, Verstraete W, Van de Wiele T. Propionate as a health-promoting microbial metabolite in the human gut. Nutr Rev. 2011 May;69(5):245-58. doi: 10.1111/j.1753-4887.2011.00388.x. PMID: 21521227
- van Deuren T, Blaak EE, Canfora EE. Butyrate to combat obesity and obesity-associated metabolic disorders: Current status and future implications for therapeutic use. Obes Rev. 2022 Oct;23(10):e13498. doi: 10.1111/obr.13498. Epub 2022 Jul 20. PMID: 35856338; PMCID: PMC9541926
- Marco Witkowski, Ina Nemet, Xinmin S Li, Jennifer Wilcox, Marc Ferrell, Hassan Alamri, Nilaksh Gupta, Zeneng Wang, Wai Hong Wilson Tang, Stanley L Hazen, Xylitol is prothrombotic and associated with cardiovascular risk, European Heart Journal, Volume 45, Issue 27, 14 July 2024, Pages 2439–2452, doi.org/10.1093/eurheartj/ehae244